He does an excellent job of explaining and motivating a useful toolbox of engineering models and methods using network-based controls.Įric Werner, Department of Physiology, Anatomy and Genetics, University of Oxford, Nature, Vol.
Nigel Goldenfeld, University of Illinois at Urbana-Champaign, Physics Today, June 2007 a superb, beautifully written and organized work that takes an engineering approach to systems biology.Īlon provides nicely written appendices to explain the basic mathematical and biological concepts clearly and succinctly without interfering with the main text.Īlon investigates networks at a higher level, including genomic regulatory networks. One final aspect that must be mentioned is the wonderful set of exercises that accompany each chapter.Īlons book should become a standard part of the training of graduate students in biological physics. He draws the detailed strands together into an appealing and inspiring overview of biology.
Yet right from chapter 1, the author succeeds in explaining in an intellectually exciting way what the cell does and what degrees of freedom enable it to function. It assumes no prior knowledge of or even interest in biology.
In order to navigate out of this carousel please use your heading shortcut key to navigate to the next or previous heading.Īlons book is the better place for physicists to start. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles.Īn Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It provides a simple mathematical framework which can be used to understand and even design biological circuits.
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